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DNMT3B Rabbit anti-Mouse, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen DNMT3B
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2943 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39900
10 μL
Each for $135.30
Add to cart
 
50-199-2942 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39899
100 μL
Each for $534.00
Add to cart
 
Description

Description

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
Specifications

Specifications

Polyclonal
Primary
DNMT3B
Unconjugated
SDS
Product Certifications
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