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DNMT3B Rabbit anti-Mouse, Unconjugated, Polyclonal, Active Motif™ 
Rabbit Polyclonal Antibody
$135.30 - $534.00
Specifications
| Monoclonal or Polyclonal | Polyclonal |
|---|---|
| Primary or Secondary | Primary |
| Antigen | DNMT3B |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
50-199-2943
|
Active Motif
39900 |
10 μL |
Each for $135.30
|
|
50-199-2942
|
Active Motif
39899 |
100 μL |
Each for $534.00
|
|
Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.Specifications
| Polyclonal | |
| Primary | |
| DNMT3B | |
| Unconjugated |
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