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Invitrogen™ DOK7 Polyclonal Antibody
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Catalog No. PIPA595620
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100 μg
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PIPA595620 100 μg
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Catalog No. PIPA595620 Supplier Invitrogen™ Supplier No. PA595620
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell, human RT4 whole cell, rat skeletal muscle tissue lysates, rat brain tissue lysates, rat heart tissue lysates, rat L6 whole cell lysates, mouse skeletal muscle tissue lysates, mouse brain tissue lysates, mouse heart tissue lysates, mouse C2C12 whole cell lysates. IHC: human skeletal muscle, rat heart. Flow: RT4 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DOK7
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene DOK7
Gene Accession No. Q18PE0, Q18PE1
Gene Alias A930013K19Rik; AW049091; C4orf25; CMS10; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; EF-12; Oit5; oncoprotein induced transcript 5; protein Dok-7; RGD1566416
Gene Symbols DOK7
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human DOK7 (STVEERVAQEALETLQLEKRLSLLSHAGR).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 231134, 285489, 305448
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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