Invitrogen™ DOPA Decarboxylase Polyclonal Antibody

Catalog No.	Quantity
PA14652	100 μL

Catalog No. PA14652 Supplier Invitrogen™ Supplier No. PA14652

Description

Rabbit Polyclonal Antibody

This antibody is specific for the ~55 kDa DDC protein in Western blots of rat adrenal medulla.

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Specifications

• Antigen: DOPA Decarboxylase
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.15 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: DDC
• Gene Accession No.: P14173, P20711, P22781, P27718
• Gene Alias: AADC; aromatic L-amino acid decarboxylase; aromatic-L-amino acid decarboxylase; aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
• Gene Symbols: DDC
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to the N-terminal region of human DDC conjugated to KLH.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100135516, 100355492, 101106765, 1644, 24311, 280762, 606852
• Target Species: Human, Rat, Canine, Rabbit, Bovine, Sheep, Guinea Pig
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG