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Lkt Laboratories CAS 25316-40-9, ≥98%, DNA intercalator and topoisomerase II inhibitor used to treat various cancers. It inhibits DNA repair by promoting histone H2AX eviction from chromatin.

Supplier: Lkt Laboratories D5794

Doxorubicin is an anthracycline that exhibits anticancer chemotherapeutic and anti-parasitic, antimalarial activities. Doxorubicin is a DNA intercalator that inhibits topoisomerase II and is clinically used to treat various cancers; it is part of the CHOP and ABVD chemotherapy regimens. Doxorubicin also promotes histone H2AX eviction from chromatin, limiting DNA repair mechanisms. Additionally, this compound inhibits growth of Plasmodium.
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