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Invitrogen™ DPM1 Polyclonal Antibody
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Catalog No. PIPA5121135
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100 μL
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PIPA5121135 100 μL
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Catalog No. PIPA5121135 Supplier Invitrogen™ Supplier No. PA5121135
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Description

Rabbit Polyclonal Antibody

Positive test controls include: NCI-H460, HeLa, SKOV3, Mouse pancreas, Mouse liver, Mouse kidney, Rat liver. The target is usually found in the following locations: Endoplasmic reticulum. Immunogen sequence: MASLEVSRSP RRSRRELEVR SPRQNKYSVL LPTYNERENL PLIVWLLVKS FSESGINYEI IIIDDGSPDG TRDVAEQLEK IYGSDRILLR PREKKLGLGT AYIHGMKHAT GNYIIIMDAD LSHHPKFIPE FIRKQKEGNF DIVSGTRYKG NGGVYGWDLK RKIISRGANF LTQILLRPGA SDLTGSFRLY RKEVLEKLIE KCVSKGYVFQ MEMIVRARQL NYTIGEVPIS FVDRVYGESK LGGNEIVSFL KGLLTLFATT.

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPM1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.44 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DPM1
Gene Accession No. O60762, O70152
Gene Alias AI118379; AI194292; CDGIE; dolichol monophosphate mannose synthase; dolichol-phosphate (beta-D) mannosyltransferase 1; Dolichol-phosphate mannose synthase; Dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase; Dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate beta-D-mannosyltransferase; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; DPM synthase; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; Dpm1; Mannose-P-dolichol synthase; Mannose-P-dolichol synthase subunit 1; MPD synthase; MPD synthase subunit 1; MPDS; OTTMUSP00000017164; P9705.3; RP23-391M18.1; SED3; YPR183W
Gene Symbols DPM1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DPM1 (NP_003850.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13480, 296394, 8813
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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