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Invitrogen™ Drebrin Monoclonal Antibody (DBN-N-03)
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Catalog No. PIMA528543
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100 μg
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Catalog No. Quantity
PIMA528543 100 μg
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Catalog No. PIMA528543 Supplier Invitrogen™ Supplier No. MA528543
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Description

Mouse Monoclonal Antibody

This antibody recognizes drebrin, an approximately 100-125 kDa intracellular regulator of actin cytoskeleton. It has also been successfully used in Mass Cytometry (CyTof).

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
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Specifications

Antigen Drebrin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone DBN-N-03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 15mM sodium azide; pH 8
Gene DBN1
Gene Accession No. Q07266, Q16643, Q9QXS6
Gene Alias D0S117E; Dbn1; developmentally regulated brain protein; developmentally-regulated brain protein; DKFZp434D064; Drba; Drebrin; drebrin 1; drebrin A; drebrin E; drebrin E2; drebrin-1; Unknown (protein for MGC:138067)
Gene Symbols DBN1
Host Species Mouse
Immunogen human drebrin (aa 1-326, N terminal).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1627, 56320, 81653
Target Species Human, Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2b
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Safety and Handling

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