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DTX2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550217

Catalog No. PA550217


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Description

Description

The antibody detects endogenous levels of total DTX2 protein.

DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Specifications

Specifications

DTX2
Polyclonal
Unconjugated
DTX2
Liquid
DTX2
Fusion protein corresponding to residues near the C terminal of human deltex homolog 2 (Drosophila)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q86UW9
KIAA1528, RNF58
Rabbit
IgG
100 μL
-20°C
Primary
113878
Documents
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