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Invitrogen™ DTX2 Polyclonal Antibody
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Catalog No. PA550217
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100 μL
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PA550217 100 μL
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Catalog No. PA550217 Supplier Invitrogen™ Supplier No. PA550217
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total DTX2 protein.

DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DTX2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene DTX2
Gene Accession No. Q86UW9
Gene Alias 2610524D08Rik; AA408415; AU022494; deltex 2 homolog; deltex 2 homolog (Drosophila); deltex 2, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 2; deltex homolog 2; deltex2; Dtx2; hDTX2; KIAA1528; mDTX2; probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; ring finger protein 58; RING-type E3 ubiquitin transferase DTX2; RNF58; zinc ion binding protein
Gene Symbols DTX2
Host Species Rabbit
Immunogen Fusion protein corresponding to residues near the C terminal of human deltex homolog 2 (Drosophila).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113878
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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