Invitrogen™ PACAP Receptor Polyclonal Antibody

Catalog No.	Quantity
PA3115	100 μL

Catalog No. PA3115 Supplier Invitrogen™ Supplier No. PA3115

Description

Rabbit Polyclonal Antibody

PA3-115 detects PAC1 in human samples. PA3-115 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40-60 kDa protein representing PAC1 in human samples. In immunohistochemistry, PAC1 immunoreactivity is predominantly localized to the plasma membrane. PA3-115 immunogen is a synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human VPAC2 receptor.

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.

Specifications

• Antigen: PACAP Receptor
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: whole serum with 0.05% sodium azide
• Gene: ADCYAP1R1
• Gene Accession No.: P41586, P70205
• Gene Alias: 2900024I10Rik; ADCYAP receptor type I; ADCYAP1 R1; ADCYAP1R 1; Adcyap1r1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 receptor 1; adenylate cyclase activating polypeptide 1 type 1 receptor; AI846590; alternatively spliced product of PACAP receptor; G-protein coupled receptor; PAC 1; PAC1; PAC1 receptor; Pac1 receptors; PAC1R; PAC1-R; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP type IA receptor; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; PACAP1-R; PACAPR; PACAPR1; PACAP-R1; PACAP-R-1; PACAPR1A; PACAP-R1A; PACAP-R-1A; PACAPRI; pituitary adenylate cyclase activating polypeptide 1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase-activating polypeptide type 1 receptor; pituitary adenylate cyclase-activating polypeptide type 1 receptor hop 1 splice variant; pituitary adenylate cyclase-activating polypeptide type I receptor; pituitary adenylate cyclase-activating polypeptide type IA receptor; pvr1
• Gene Symbols: ADCYAP1R1
• Host Species: Rabbit
• Immunogen: Synthetic peptide, KLH conjugated, corresponding to the residues L (450) S K S S S Q I R M S G L P A D N L A T(468) of human PAC1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11517, 117
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov