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DUSP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735643 Shop All Proteintech Group Inc Products
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50-173-5643 150 μL
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Catalog No. 50-173-5643 Supplier Proteintech Group Inc Supplier No. 273271AP150UL
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predomitly expressed in hematopoietic tissues, and is localized in the nucleus.

Specifications

Antigen DUSP2
Applications Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DUSP2
Gene Accession No. Q05922, Q05923
Gene Alias dual specificity phosphatase 2, DUSP2, PAC 1, PAC1
Gene Symbols DUSP2
Host Species Rabbit
Immunogen DUSP2 Fusion Protein Ag25380
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13537, 1844
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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