Invitrogen™ Dynamin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143374

Catalog No. PIPA5143374

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Specifications

• Antigen: Dynamin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: b2b2159Clo; CMT2M; CMTDI1; CMTDIB; DI-CMTB; Dnm2; DYIIAAB; Dyn2; dynamin 2; dynamin II; Dynamin UDNM; Dynamin-2; DYNII; LCCS5; Udnm
• Immunogen: The immunogen used to generate this antibody corresponds to zebrafish Dnm2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Concentration: 0.9 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG