Dynamitin (1-401 AA) Mouse anti-Human, Mouse, Clone: 2B9A5, Proteintech

Catalog No.	Quantity
50-173-6354	150 μL

Catalog No. 50-173-6354 Supplier Proteintech Group Inc Supplier No. 602571IG150UL

Description

Mouse Monoclonal Antibody

This antibody is against the N terminal 86aa of full length p50 dynamitin.

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: Dynamitin (1-401 AA)
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2B9A5
• Concentration: 1.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: DCTN2
• Gene Accession No.: Q13561, Q99KJ8
• Gene Alias: DCTN2, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin
• Gene Symbols: Dctn2
• Host Species: Mouse
• Immunogen: Dynamitin (1-401 AA) Fusion Protein Ag1902
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10540, 69654
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG3