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Cayman Chemical DYRK1A InhIbItr comp 11 10mg
SDP

Supplier:  Cayman Chemical 4171510 MG

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A PTH1R agonist selectively induces cAMP production in COS-7 cells expressing human PTH1R (EC50 2.4 UM) over COS-7 cells expressing human PTH2R (EC50 100 UM) induces calcium release from isolated fetal rat long bones at 1 and 3 UM increases lumbar spine and proximal femur BMD lumbar spine bone strength serum levels of osteocalcin and bone formation in the lumbar spine without affecting serum calcium levels in an OVX rat model of osteopenia at 10 mg/kg per day increases serum but not urinary calcium levels in a TPTX rat model of hypothyroidism at 9 mg/kg

Catalog No. 50-294-3417


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