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Invitrogen™ DYRK3 Polyclonal Antibody
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Catalog No. PIPA5111727
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100 μL
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PIPA5111727 100 μL
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Catalog No. PIPA5111727 Supplier Invitrogen™ Supplier No. PA5111727
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GVYDTFMMID ETKCPPCSNV LCNPSEPPPP RRLNMTTEQF TGDHTQHFLD GGEMKVEQLF QEFGNRKSNT IQ Highest antigen sequence indentity to the following orthologs: Mouse - 74%, Rat - 75%.

DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYRK3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DYRK3
Gene Accession No. O43781
Gene Alias BC006704; dual specificity tyrosine phosphorylation regulated kinase 3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual specificity tyrosine-phosphorylation-regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5; dyrk3; dyrk3 {ECO:0000312; DYRK5; EMBL:AAH97474.1}; hYAK3-2; KSR; protein kinase Dyrk3; RED; REDK; regulatory erythroid kinase; RP11-343H5.2; RSU2
Gene Symbols DYRK3
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human DYRK3. Recombinant protein control fragment (Product #RP-108031).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8444
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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