Invitrogen™ Dystrophin Recombinant Rabbit Monoclonal Antibody (10G10K7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542861

Catalog No. PIMA542861

Description

Immunogen sequence: LESQLHRLRQ LLEQPQAEAK VNGTTVSSPS TSLQRSDSSQ PMLLRVVGSQ TSDSMGEEDL LSPPQDTSTG LEEVMEQLNN SFPSSRGRNT PGKPMREDTM.

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Specifications

• Antigen: Dystrophin
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11530, P11531
• Gene Symbols: DMD
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: 10G10K7
• Conjugate: Unconjugated
• Gene: DMD
• Gene Alias: apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13405, 24907
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov