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Invitrogen™ Dystrophin Recombinant Rabbit Monoclonal Antibody (10G10K7)
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Catalog No. PIMA542861
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100 μL
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PIMA542861 100 μL
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Catalog No. PIMA542861 Supplier Invitrogen™ Supplier No. MA542861
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: LESQLHRLRQ LLEQPQAEAK VNGTTVSSPS TSLQRSDSSQ PMLLRVVGSQ TSDSMGEEDL LSPPQDTSTG LEEVMEQLNN SFPSSRGRNT PGKPMREDTM.

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dystrophin
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Recombinant Monoclonal
Clone 10G10K7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DMD
Gene Accession No. P11530, P11531
Gene Alias apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
Gene Symbols DMD
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13405, 24907
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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