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Abcam E-4031 Dihydrochloride, HERG K+ Channel Blocker, 99% Purity, Solid, 5 mg

Catalog No. 502584672
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50-258-4672 5 mg
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Catalog No. 50-258-4672 Supplier Abcam Supplier No. AB1201585MG
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Description

Type III antiarrhythmic drug that blocks ion channels encoded by the ether-a-go-go related gene (ERG1 or KCNH1).

  • Molecular Weight: 474.4 Da
  • Purity: >99%
  • Physical State: Solid
  • Activity: Type III antiarrhythmic drug that blocks ion channels encoded by the ether-a-go-go related gene (ERG1 or KCNH1). Blocks channels in the open configuration with little effect on the channels in the closed configuration. The IC50 for block of human ERG channels in expression systems is approx. 350 nM.
  • Storage: Store at +4°C.
  • Constituents: 100% N-(4-{1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl}phenyl)methanesulfonamide dihydrochloride

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule HERG K+ Channel
Substrate Properties Chemical Substrate
Shipping Condition Ambient
Format Vial
Product Type Antioxidant
Form Solid
Quantity 5 mg
For Use With (Application) Ion channel blocking
Storage Requirements Store at 4°C.
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