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Diagnostic Biosystems E2F-1 TRANSCRIPTION FACTOR E2F-1 Transcription Factor
Supplier: Diagnostic Biosystems MOB38101

This antibody reacts with a protein of 60 kDa. E2Fs are DNAbinding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F-1 is proposed to be involved in several cellular processes that range from tumor suppression, cell progression and oncogenesis. E2F-1 over expression can also drive cells into apoptosis.
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