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Invitrogen™ E2F2 Polyclonal Antibody
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Catalog No. PIPA577950
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100 μL
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PIPA577950 100 μL
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Catalog No. PIPA577950 Supplier Invitrogen™ Supplier No. PA577950
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Description

Rabbit Polyclonal Antibody

Positive Control: 293T, 293T nuclear extract, K562, K562 nuclear extract Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.93 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene E2F2
Gene Accession No. Q14209
Gene Alias E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2
Gene Symbols E2F2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human E2F2. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1870
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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