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Invitrogen™ E2F3 Monoclonal Antibody (PG30)
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Catalog No. PIMA125333
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100 μL
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Catalog No. Quantity
PIMA125333 100 μL
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Catalog No. PIMA125333 Supplier Invitrogen™ Supplier No. MA125333
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Description

Mouse Monoclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F3
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone PG30
Concentration 2.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 15 mM sodium azide; pH 7.4
Gene E2F3
Gene Accession No. O00716
Gene Alias DKFZp686C18211; E2F transcription factor 3; E2f3; E2F-3; E2f3a; E2F3b; KIAA0075; MGC104598; RGD1561600; RP1-177P22.2; Transcription factor E2F3
Gene Symbols E2F3
Host Species Mouse
Immunogen Recombinant human E2F3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1871
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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