E2F3 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5717	150 μL

Catalog No. 50-173-5717 Supplier Proteintech Group Inc Supplier No. 276151AP150UL

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.

Specifications

• Antigen: E2F3
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: E2F3
• Gene Accession No.: O00716
• Gene Alias: E2F 3, E2F transcription factor 3, E2F3, KIAA0075, Transcription factor E2F3
• Gene Symbols: E2F3
• Host Species: Rabbit
• Immunogen: E2F3 Fusion Protein Ag26367
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1871
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG