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Invitrogen™ EAP30 Polyclonal Antibody
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Catalog No. PIPA587999
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100 μL
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PIPA587999 100 μL
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Catalog No. PIPA587999 Supplier Invitrogen™ Supplier No. PA587999
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Rabbit Polyclonal Antibody

Immunogen sequence: MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF ASKHKQEIRK NPEFRVQFQD MCATIGVDPL ASGKGFWSEM LGVGDFYYEL GVQIIEVCLA LKHRNGGLIT LEELHQQVLK GRGKFAQDVS QDDLIRAIKK LKALGTGFGI IPVGGTYLIQ SVPAELNMDH TVVLQLAEKN GYVTVSEIKA SLKWETERAR QVLEHLLKEG LAWLDLQAPG EAHYWLPALF TDLYSQEITA EEAREALP; Positive Samples: 293T, Mouse brain; Cellular Location: Cytoplasm, Endosome membrane, Late endosome membrane, Nucleus.

ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EAP30
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SNF8
Gene Accession No. Q96H20, Q9CZ28
Gene Alias D11Moh34; Dot3; Eap30; EAP30 subunit of ELL complex; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; hVps22; RGD1310144; si:dkey-220f10.1; snf8; SNF8 subunit of ESCRT-II; SNF8, ESCRT-II complex subunit; SNF8, ESCRT-II complex subunit, homolog; SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae); vacuolar sorting snf8 ELL associated of 30kDa; vacuolar-sorting protein SNF8; VPS22; zgc:101578
Gene Symbols SNF8
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human SNF8 (NP_0091722).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11267, 27681
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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