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Invitrogen™ EB1 Monoclonal Antibody (1A11/4)
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Catalog No. 412100
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Catalog No. Quantity
41-210-0 100 μg
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Catalog No. 41-210-0 Supplier Invitrogen™ Supplier No. 412100
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Description

Mouse Monoclonal Antibody

EB1 Monoclonal Antibody for Western Blot, ICC/IF, ELISA

EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively. EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11. 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia. EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EB1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1A11/4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene Mapre1
Gene Accession No. Q15691, Q61166, Q66HR2
Gene Alias 5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
Gene Symbols Mapre1
Host Species Mouse
Immunogen Recombinant protein encompassing the N-terminal domain of the human EB1 protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100685707, 114764, 13589, 22919
Target Species Canine, Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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