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Invitrogen™ EBF2 Polyclonal Antibody
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Catalog No. PIPA5140080
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100 μL
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PIPA5140080 100 μL
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Catalog No. PIPA5140080 Supplier Invitrogen™ Supplier No. PA5140080
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: PGFLNGSPTG SPYGIMSSSP TVGSSSTSSI LPF Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Early B-cell factor 2 (EBF2) is a gene located on chromosome 8p11.23, encoding a transcription factor involved in the regulation of gene expression during neural and adipose tissue development. EBF2 belongs to the COE family of transcription factors and plays a pivotal role in cellular differentiation processes. In the nervous system, EBF2 is essential for the development and function of neurons, particularly in regions like the olfactory system. Additionally, EBF2 is involved in adipogenesis, where it regulates genes responsible for the differentiation of brown adipocytes, contributing to thermogenesis and energy metabolism. Dysfunction or altered expression of EBF2 can impact neurological function and metabolic homeostasis, potentially influencing conditions such as obesity, diabetes, and neurodevelopmental disorders. Research into EBF2 is exploring its role in these physiological contexts and the implications of its regulatory mechanisms, offering insights into potential therapeutic approaches.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EBF2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EBF2
Gene Accession No. Q9HAK2
Gene Alias COE2; Collier, Olf and EBF 2; D14Ggc1e; early B cell factor 2; early B-cell factor 2; Ebf2; EBF-2; metencephalon-mesencephalnon-olfactory transcription factor 1; metencephalon-mesencephalon-olfactory transcription factor 1; MET-mesencephalon-olfactory TF1; MET-mesencephalon-olfactory transcription factor 1; Mmot1; O/E-3; OE-3; Olf-1/EBF-like 3; transcription factor COE2
Gene Symbols EBF2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EBF2. Recombinant protein control fragment (Product #RP-108918).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64641
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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