Invitrogen™ ECEL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527951

Catalog No. PIPA527951

Description

Recommended positive controls: ECEL1 tansfected 293T cell. Predicted reactivity: Mouse (95%), Rat (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

Specifications

• Antigen: ECEL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ECEL1
• Gene Alias: DA5D; damage induced neuronal endopeptidase; damage-induced neuronal endopeptidase; Dine; ECEL1; ECEX; endothelin converting enzyme like 1; endothelin converting enzyme-like 1; endothelin-converting enzyme-like 1; metallopeptidase; UNQ2431/PRO4991; X converting enzyme; XCE; Xce protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9427
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.4 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O95672
• Gene Symbols: ECEL1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 274 and 633 of Human ECEL1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG