Invitrogen™ EHHADH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537009

Catalog No. PIPA537009

Description

This antibody detects endogenous protein at a molecular weight of 79 kDa. Purity is >95% by SDS-PAGE.

As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.

Specifications

• Antigen: EHHADH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EHHADH
• Gene Alias: 1; 1300002P22Rik; 3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; ECHD; EHHADH; Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; FRTS3; HD; L-3-hydroxyacyl-CoA dehydrogenase; LBFP; L-bifunctional enzyme; L-bifunctional protein, peroxisomal; Lbp; L-PBE; L-specific bifunctional protein; L-specific multifunctional beta-oxdiation protein; MEF; Mfe; Mfe1; MFP; MFP1; multifunctional enzyme type 1; Pbe; PBFE; perMFE-1; Peroxisomal bifunctional enzyme; peroxisomal bifunctional enzyme type 1; peroxisomal enoyl-CoA hydratase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171142, 1962, 74147
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P07896, Q08426, Q9DBM2
• Gene Symbols: EHHADH
• Immunogen: Synthetic peptide corresponding to amino acids 518-563 of human EHHADH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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