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Invitrogen™ EHHADH Polyclonal Antibody
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Catalog No. PIPA583586
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100 μL
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PIPA583586 100 μL
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Catalog No. PIPA583586 Supplier Invitrogen™ Supplier No. PA583586
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ILGEGIAASP EHIDVVYLHG YGWPRHKGGP MFYASTVGLP TVLEKLQKYY RQNPDIPQLE PSDYLKKLAS QGNPPLKE Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 85%.

As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EHHADH
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EHHADH
Gene Accession No. Q08426
Gene Alias 1; 1300002P22Rik; 3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; ECHD; EHHADH; Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; FRTS3; HD; L-3-hydroxyacyl-CoA dehydrogenase; LBFP; L-bifunctional enzyme; L-bifunctional protein, peroxisomal; Lbp; L-PBE; L-specific bifunctional protein; L-specific multifunctional beta-oxdiation protein; MEF; Mfe; Mfe1; MFP; MFP1; multifunctional enzyme type 1; Pbe; PBFE; perMFE-1; Peroxisomal bifunctional enzyme; peroxisomal bifunctional enzyme type 1; peroxisomal enoyl-CoA hydratase
Gene Symbols EHHADH
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EHHADH. Recombinant protein control fragment (Product #RP-103761).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1962
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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