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Invitrogen™ EFHC2 Polyclonal Antibody
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Catalog No. PIPA556951
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PIPA556951 100 μL
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Catalog No. PIPA556951 Supplier Invitrogen™ Supplier No. PA556951
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KEKFHKSQHW GFCNNVMMLV SDEKPGIGGE PLLGQKIKPK CSIYPKGDGS DVPSWVAFDK QVLSFDAYLE EEVLDKSQTN YRIR Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.

EFHC2 (EF-hand domain-containing protein 2) is a gene located on the X chromosome at position Xp11.4. The protein encoded by EFHC2 is characterized by the presence of EF-hand motifs, which are helix-loop-helix structural domains capable of binding calcium ions. The EFHC2 protein is involved in various cellular processes, particularly those that are calcium-dependent, such as signal transduction and regulation of enzyme activities. EFHC2 has been implicated in neurological functions and conditions. For instance, it has been studied in the context of epilepsy, where variants in the gene are associated with increased susceptibility to juvenile myoclonic epilepsy. Additionally, EFHC2 is expressed in the brain and testis, suggesting roles in neurodevelopment and reproduction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EFHC2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EFHC2
Gene Accession No. Q5JST6, Q9D485
Gene Alias 4933407D04Rik; dJ1158H2.1; EF-hand domain (C-terminal) containing 2; EF-hand domain containing 2; EF-hand domain-containing family member C2; Efhc2; mental retardation, X-linked 74; mRib72-2; MRX74
Gene Symbols EFHC2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EFHC2. Recombinant protein control fragment (Product #RP-95475).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74405, 80258
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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