EHMT1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301642AT

Catalog No. 50-156-0890

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates ′Lys-9′ of histone H3 in vitro. H3 ′Lys-9′ methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

Specifications

• Antigen: EHMT1
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q9H9B1
• Gene Symbols: EHMT1
• Immunogen: Between 25 and 75
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene: EHMT1
• Gene Alias: Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP1; Lysine N-methyltransferase 1D; EHMT1; EUHMTASE1; KIAA1876; KMT1D
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79813
• Content And Storage: 4° C
• Form: Liquid