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STEMCELL Technologies EHNA (Hydrochloride), Size: 5 mg

Supplier: STEMCELL Technologies 72442

EHNA is a reversible adenosine deaminase inhibitor (IC₅₀ = 1.2 μM in human red blood cells) that also selectively inhibits the cGMP-specific phosphodiesterase (PDE2) (IC₅₀ = 0.8 and 2 μM from human and porcine myocardium, respectively, 3.5 μM in rat hepatocyte, and 5.5 μM in human platelet) (Michie et al.; Podzuweit et al.). MAINTENANCE AND SELF-RENEWAL· Maintains pluripotency of human embryonic stem cells in the absence of exogenous cytokines, and blocks directed neuronal differentiation (Burton et al.).
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