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Invitrogen™ eIF2 gamma Polyclonal Antibody
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Catalog No. PIPA592081
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100 μL
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PIPA592081 100 μL
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Catalog No. PIPA592081 Supplier Invitrogen™ Supplier No. PA592081
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLAAIEIMKL KHILILQNKI DLVKESQAKE QYEQILAFVQ GTVAEGAPII PISAQLKYNI EVVCEYIVKK IPVPPRDFTS EPRLIVIRSF DVNKPGCEVD DLKGGVAGGS ILKGVLKVGQ EIEVRPGIVS KDSEGKLMCK PIFSKIVSLF AEHNDLQYAA PGGLIGVGTK IDPTLCRADR MVGQVLGAVG ALPEIFTELE ISYFLLRRLL GVRTEGDKKA AKVQKLSKNE VLMVNIGSLS TGGRVSAVKA DLGKIVLTNP VCTEVGEKIA LSRRVEKHWR LIGWGQIRRG VTIKPTVDDD; Positive Samples: Rat brain.

The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2 alpha, eIF2 beta and eIF2 gamma (eukaryotic translation initiation factor 2 alpha, beta and gamma, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein that belongs to the gamma subfamily of GTP-binding elongation factor proteins. Existing as a heterotrimer composed of an alpha, beta and gamma chain, eIF2S3 functions to bind ribosomal subunits and catalyze the subsequent formation of preinitiation complexes necessary for protein synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF2 gamma
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EIF2S3
Gene Accession No. P81795
Gene Alias EIF2; EIF2G; eIF-2gA; EIF2gamma; eIF-2-gamma; eIF-2-gamma X; eIF-2gX; Eif2s3; Eif2s3x; Eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initiation factor 2 subunit 3, X-linked; Eukaryotic translation initiation factor 2 subunit gamma; eukaryotic translation initiation factor 2 subunit gamma X; Eukaryotic translation initiation factor 2 subunit gamma, X-linked; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked; eukaryotic translation initiation factor 2G; PP42
Gene Symbols EIF2S3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human EIF2S3 (NP_0014061).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 299027
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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