Invitrogen™ EIF2S1 Monoclonal Antibody (EIF2-alpha)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ AHO0802

Catalog No. AHO0802

Description

This antibody recognizes the alpha subunit of eukaryotic translation initiation factor 2 (EIF2-alpha). Recommended positive control are human Jurkat, CEM, and HeLa cells; mouse 3T3L1 cells; and rat PC-12 cells.

EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.

Specifications

• Antigen: EIF2S1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: P05198, P68101, Q6ZWX6
• Gene Symbols: EIF2S1
• Immunogen: Recombinant human eIF-2-alpha.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry
• Clone: EIF2-alpha
• Conjugate: Unconjugated
• Gene: EIF2S1
• Gene Alias: 0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 13665, 1965, 54318
• Content And Storage: -20°C
• Form: Liquid
• Green Features: Responsibly packaged

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov