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Invitrogen™ EIF2S1 Monoclonal Antibody (EIF2-alpha)
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Catalog No. AHO0802
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Catalog No. Quantity
AHO0802 100 μg
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Catalog No. AHO0802 Supplier Invitrogen™ Supplier No. AHO0802
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Description

Mouse Monoclonal Antibody

This antibody recognizes the alpha subunit of eukaryotic translation initiation factor 2 (EIF2-alpha). Recommended positive control are human Jurkat, CEM, and HeLa cells; mouse 3T3L1 cells; and rat PC-12 cells.

EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
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Specifications

Antigen EIF2S1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone EIF2-alpha
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene EIF2S1
Gene Accession No. P05198, P68101, Q6ZWX6
Gene Alias 0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01
Gene Symbols EIF2S1
Host Species Mouse
Immunogen Recombinant human eIF-2-alpha.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13665, 1965, 54318
Target Species Human, Mouse, Monkey, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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