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eIF3C/eIF3S8 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501557487
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50-155-7487 20 μL
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Catalog No. 50-155-7487 Supplier Bethyl Laboratories, Inc Supplier No. A300377AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Orangutan

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Specifications

Antigen eIF3C/eIF3S8
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene EIF3C
Gene Accession No. Q99613
Gene Alias cell migration-inducing protein 17; eIF3 p110; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa
Gene Symbols EIF3C
Host Species Rabbit
Immunogen Between 850 and 918
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8663
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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