eIF3C/eIF3S8 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-155-7485	100 μL

Catalog No. 50-155-7485

Supplier: Bethyl Laboratories, Inc A300377A

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Orangutan

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Specifications

• Antigen: eIF3C/eIF3S8
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: EIF3C
• Gene Accession No.: Q99613
• Gene Alias: cell migration-inducing protein 17; eIF3 p110; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa
• Gene Symbols: EIF3C
• Host Species: Rabbit
• Immunogen: Between 850 and 918
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8663
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG