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eIF3D/EIF3S7 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301758A

Encompass_Preferred

Catalog No. 50-155-9625


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Orangutan

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
Specifications

Specifications

eIF3D/EIF3S7
Polyclonal
Unconjugated
EIF3D
RP5-1119A7.12-003, EIF3S7, eIF3-p66, eIF3-zeta, eIF-3-zeta, eIF3 p66, eukaryotic translation initiation factor 3 subunit 7, eukaryotic translation initiation factor 3 subunit D, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa, translation initiation factor eIF3 p66 subunit
Rabbit
Antigen affinity chromatography
RUO
8664
4° C
Liquid
Immunoprecipitation, Western Blot
0.2 mg/ml
TBS with 0.1% BSA and 0.09% sodium azide
O15371
EIF3D
Between 150 and 200
100 μL
Primary
Human
Antibody
IgG
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