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eIF3D/EIF3S7 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A301758A

Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Orangutan
eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.Specifications
eIF3D/EIF3S7 | |
Polyclonal | |
Unconjugated | |
EIF3D | |
RP5-1119A7.12-003, EIF3S7, eIF3-p66, eIF3-zeta, eIF-3-zeta, eIF3 p66, eukaryotic translation initiation factor 3 subunit 7, eukaryotic translation initiation factor 3 subunit D, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa, translation initiation factor eIF3 p66 subunit | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8664 | |
4° C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.2 mg/ml | |
TBS with 0.1% BSA and 0.09% sodium azide | |
O15371 | |
EIF3D | |
Between 150 and 200 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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