EIF3D Monoclonal Antibody (OTI1G10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808188

Catalog No. 50-168-1957

Description

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.

Specifications

• Antigen: EIF3D
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O15371
• Gene Symbols: EIF3D
• Immunogen: Full length human recombit protein of human EIF3D produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1G10
• Conjugate: Unconjugated
• Gene: EIF3D
• Gene Alias: EIF3S7, eIF3-p66, eIF3-zeta
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8664
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid