EIF3D Mouse anti-Human, Mouse, Rat, Clone: 2C5A3, Proteintech

Catalog No.	Quantity
50-173-6466	150 μL

Catalog No. 50-173-6466 Supplier Proteintech Group Inc Supplier No. 660241IG150UL

Description

Mouse Monoclonal Antibody

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.

Specifications

• Antigen: EIF3D
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2C5A3
• Concentration: 0.78 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: EIF3D
• Gene Accession No.: O15371, O70194, Q6AYK8
• Gene Alias: eIF 3 zeta, eIF3 p66, eIF3 zeta, EIF3D, EIF3S7
• Gene Symbols: Eif3d
• Host Species: Mouse
• Immunogen: EIF3D Fusion Protein Ag18092
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 362952, 55944, 8664
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b