Invitrogen™ eIF3g Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541775

Catalog No. PIPA541775

Description

Peptide sequence: SPEPELLPGA PLPPPKEVIN GNIKTVTEYK IDEDGKKFKI VRTFRIETRK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 79%.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.

Specifications

• Antigen: eIF3g
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF3G
• Gene Alias: 44kDa; D0Jmb4; eiF3 delta; eIF3 p42; eIF3 p42 {ECO:0000255; eIF3 p44; eIF3 p44 {ECO:0000255; eIF-3 RNA-binding subunit; eIF-3 RNA-binding subunit {ECO:0000255; eIF-3-delta; eIF3-delta; eIF-3-delta {ECO:0000255; EIF3G; eIF3g {ECO:0000255; Eif3p42; EIF3-P42; eIF3-p44; EIF3S4; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255; eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3 subunit G {ECO:0000255; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3, subunit 4 delta; eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3, subunit G; HAMAP-Rule:MF_03006}; p44; similar to eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; translation initiation factor eIF3-p44; TU-189B2; Unknown (protein for MGC:128341); zgc:56553
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8666
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O75821
• Gene Symbols: EIF3G
• Immunogen: Synthetic peptide directed towards the N-terminal of human EIF3S4 (aa 42-91).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG