Invitrogen™ eIF3g Polyclonal Antibody

Catalog No.	Quantity
PIPA583585	100 μL

Catalog No. PIPA583585 Supplier Invitrogen™ Supplier No. PA583585

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ICKGDHWTTR CPYKDTLGPM QKELAEQLGL STGEKEKLPG ELEPVQATQN KTGKYVPPSL RDGASRRGES MQPN Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 97%.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.

Specifications

• Antigen: eIF3g
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: EIF3G
• Gene Accession No.: O75821
• Gene Alias: 44kDa; D0Jmb4; eiF3 delta; eIF3 p42; eIF3 p42 {ECO:0000255; eIF3 p44; eIF3 p44 {ECO:0000255; eIF-3 RNA-binding subunit; eIF-3 RNA-binding subunit {ECO:0000255; eIF-3-delta; eIF3-delta; eIF-3-delta {ECO:0000255; EIF3G; eIF3g {ECO:0000255; Eif3p42; EIF3-P42; eIF3-p44; EIF3S4; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255; eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3 subunit G {ECO:0000255; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3, subunit 4 delta; eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3, subunit G; HAMAP-Rule:MF_03006}; p44; similar to eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; translation initiation factor eIF3-p44; TU-189B2; Unknown (protein for MGC:128341); zgc:56553
• Gene Symbols: EIF3G
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human EIF3G. Recombinant protein control fragment (Product #RP-99099).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8666
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG