Invitrogen™ eIF4A3 Recombinant Rabbit Monoclonal Antibody (17H5L19)

Catalog No.	Quantity
PI702545	100 μg

Catalog No. PI702545 Supplier Invitrogen™ Supplier No. 702545

Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rat, Sheep, Pig, Bovine Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

eIF4A3 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. eIF4A3 is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Specifications

• Antigen: eIF4A3
• Applications: Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 17H5L19
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: EIF4A3
• Gene Accession No.: P38919, Q91VC3
• Gene Alias: 2400003O03Rik; ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-3; Ddx48; DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; DEAD box protein 48; Eif4a3; eIF4AIII; eIF-4A-III; eIF4A-III; eukaryotic initiation factor 4AIII; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-III, N-terminally processed; Eukaryotic initiation factor 4A-III-like protein; eukaryotic initiation factor 4A-like NUK-34; eukaryotic translation initiation factor 4A; Eukaryotic translation initiation factor 4A isoform 3; eukaryotic translation initiation factor 4A, isoform 3; eukaryotic translation initiation factor 4A3; hNMP 265; KIAA0111; mKIAA0111; MUK34; NMP 265; NMP265; Nuclear matrix protein 265; NUK34; RCPS; similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; zgc:56139
• Gene Symbols: EIF4A3
• Host Species: Rabbit
• Immunogen: Peptides corresponding to human eIF4A3 (aa 15-33, 302-318).
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 192170, 9775
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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