Invitrogen™ eIF5A Monoclonal Antibody (4E10G8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1179

Catalog No. PIMA1179

Description

MA1-179 detects EIF5A from human samples. MA1-179 has been successfully used in western blot, immunofluorescence, and flow cytometry applications.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Specifications

• Antigen: eIF5A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P63241
• Gene Symbols: EIF5A
• Immunogen: Purified recombinant, full length human EIF5A (aa1-154) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 4E10G8
• Conjugate: Unconjugated
• Gene: EIF5A
• Gene Alias: AA410058; D19Wsu54e; Eif4d; eIF-4D; Eif5a; eIF-5A; EIF5A1; eIF-5A1; eIF-5A-1; eIF5AI; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1984
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid