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Invitrogen™ eIF5A Monoclonal Antibody (4E10G8)
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Catalog No. PIMA1179
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100 μg
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Catalog No. Quantity
PIMA1179 100 μg
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Catalog No. PIMA1179 Supplier Invitrogen™ Supplier No. MA1179
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Mouse Monoclonal Antibody

MA1-179 detects EIF5A from human samples. MA1-179 has been successfully used in western blot, immunofluorescence, and flow cytometry applications.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF5A
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4E10G8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4
Gene EIF5A
Gene Accession No. P63241
Gene Alias AA410058; D19Wsu54e; Eif4d; eIF-4D; Eif5a; eIF-5A; EIF5A1; eIF-5A1; eIF-5A-1; eIF5AI; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A
Gene Symbols EIF5A
Host Species Mouse
Immunogen Purified recombinant, full length human EIF5A (aa1-154) expressed in E. Coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1984
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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