EIF5B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8809	Proteintech Group Inc 135271AP150UL	150 μL

Description

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Specifications

• Antigen: EIF5B
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: B2GUV7, O60841, Q05D44
• Gene ID (Entrez): 226982, 308306, 9669
• Immunogen: EIF5B Fusion Protein Ag4404
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: EIF5B

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: eIF 5B, EIF5B, IF2, KIAA0741
• Gene Symbols: EIF5B
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody