MilliporeSigma™ Elastase, Human Neutrophil, Protein

Description

Native elastase from human neutrophil. A serine protease that degrades elastin, collagen, and proteoglycans. Its overexpression has been implicated in the development of pulmonary emphysema, rheumatoid arthritis, and cystic fibrosis.

Specifications

• Formulation: Salt-free.
• Preparation Method: Reconstitute in 50mM sodium acetate, pH 5.5, with 200mM NaCl or in other aqueous buffers. Material is most active near a neutral pH, but to maintain stability upon reconstitution, use in a slightly acidic buffer (pH 5.5) to avoid autolysis.
• Purification Method: Major band by SDS-PAGE
• Quantity: 100 μg
• Immunogen: Elastase
• Storage Requirements: Following reconstitution, aliquot and freeze (−20°C) for long term storage or refrigerate (4°C) for short-term storage. Acidic stock solutions are stable for up to 1 month at 4°C or for up to 1 year at −20°C.
• Regulatory Status: RUO
• Species: Human
• Recombinant: Native
• Form: Lyophilized