ELK1 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5664	150 μL

Catalog No. 50-173-5664 Supplier Proteintech Group Inc Supplier No. 274201AP150UL

Description

Rabbit Polyclonal Antibody

The transcription factor Elk1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus. Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by Elk1. Elk1 appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1 phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo.

Specifications

• Antigen: ELK1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.6 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: ELK1
• Gene Accession No.: P19419
• Gene Alias: ELK1
• Gene Symbols: ELK1
• Host Species: Rabbit
• Immunogen: ELK1 Fusion Protein Ag26683
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2002
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG