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Invitrogen™ ELOVL1 Polyclonal Antibody
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Catalog No. PIPA5104373
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PIPA5104373 100 μL
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Catalog No. PIPA5104373 Supplier Invitrogen™ Supplier No. PA5104373
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ELOVL1.

Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELOVL1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ELOVL1
Gene Accession No. Q9BW60, Q9JLJ5
Gene Alias 3-keto acyl-CoA synthase ELOVL1; AA407424; BB151133; CGI88; CGI-88; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; elongation of very long chain fatty acids protein 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; sequence similarity to Cig30 1; Ssc1; Very long chain 3-ketoacyl-CoA synthase 1; very long chain 3-oxoacyl-CoA synthase 1; very-long-chain 3-oxoacyl-CoA synthase 1
Gene Symbols ELOVL1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ELOVL1(Accession Q9BW60), corresponding to amino acid residues V108-I158.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54325, 64834
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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