Invitrogen™ EMAP II Monoclonal Antibody (546-2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA140228

Catalog No. 01-676-568

Description

MA1-40228 detects EMAP-II from human and rat samples. MA1-40228 has been successfully used in ELISA, flow cytometry, immunohistochemistry (paraffin), and Western blot applications. The MA1-40228 immunogen is human EMAP-II polypeptide.

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Specifications

• Antigen: EMAP II
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: Q12904
• Gene Symbols: Aimp1
• Immunogen: Recombinant human EMAP-II.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 546-2
• Conjugate: Unconjugated
• Gene: Aimp1
• Gene Alias: 9830137A06Rik; aaRS-interacting multifunctional protein 1; AIMP1; AIMP1/p43; AIMP1-PA; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; aminoacyl-tRNA synthetase-interacting multifunctional protein 1; ARS inducible multifunctional protein 1; ARS-interacting multifunctional protein 1; CG8235; CG8235-PA; Dmel\CG8235; Dmel_CG8235; EMAP2; EMAP-2; EMAPII; EMAP-II; endothelial monocyte activating polypeptide 2; endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; endothelial-monocyte activating polypeptide II; HLD3; mca1; multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; p43; SCYE1; Small inducible cytokine subfamily E member 1; small inducible cytokine subfamily E, member 1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 114632, 9255
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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