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Invitrogen™ Embigin Polyclonal Antibody
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Catalog No. PIPA532744
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50 μg
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PIPA532744 50 μg
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Catalog No. PIPA532744 Supplier Invitrogen™ Supplier No. PA532744
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Orangutan (94%); Gibbon, Marmoset, Bat (88%); Bovine, Dog (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Embigin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene EMB
Gene Accession No. Q6PCB8
Gene Alias AL022799; EMB; Embigin; embigin homolog; glycoprotein 70; Gp70; Teratocarcinoma glycoprotein Gp-70
Gene Symbols EMB
Host Species Rabbit
Immunogen Synthetic 17 amino acid peptide from C-Terminus of human EMB.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133418
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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