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MilliporeSigma™ Complement C3a des-Arg, Human, Protein

Catalog No. 20488450UG Shop All MilliporeSigma Products
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20-488-450UG 50 μg
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Catalog No. 20-488-450UG Supplier MilliporeSigma™ Supplier No. 20488450UG
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Description

Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide.
TRUSTED_SUSTAINABILITY

Specifications

Concentration Concentration on Label
Formulation In PBS, pH 7.2.
Purification Method SDS-PAGE
Quantity 50 μg
Immunogen Complement C3a des-Arg
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Human
Recombinant Native
Form Liquid
Purity or Quality Grade ≥90%
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