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MilliporeSigma™ Factor B, Human, Protein

Catalog No. 341262250UG Shop All MilliporeSigma Products
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Catalog No. Quantity
34-126-2250UG 250 μg
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Catalog No. 34-126-2250UG Supplier MilliporeSigma™ Supplier No. 341262250UG
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Description

Native factor B from human serum. Single-chain glycoprotein present in normal human serum at about 200μg/mL. During activation of complement via the alternative pathway, Factor B is cleaved and thus activated by Factor D into two fragments of M.W. of 30kDa (Ba) and 63kDa (Bb). The Bb fragment contains the serine protease enzymatic active site. The activated Bb fragment continues activation via the alternative pathway by cleaving, and thus activating, C3 and C5.
TRUSTED_SUSTAINABILITY

Specifications

Formulation In PBS, pH 7.2.
Purification Method SDS-PAGE
Quantity 250 μg
Immunogen Factor B
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Human
Recombinant Native
Form Liquid
Purity or Quality Grade ≥90%
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