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MilliporeSigma™ Kininogen, High Molecular Weight, Single Chain, Human Plasma, Protein, Calbiochem

Catalog No. 4226861MG Shop All MilliporeSigma Products
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42-268-61MG 1mg
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Description

Native, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
TRUSTED_SUSTAINABILITY

Specifications

Concentration Concentration on Label
Formulation In 150mM NaCl, 4mM sodium acetate buffer, pH 5.3.
Purification Method SDS-PAGE
Quantity 1mg
Immunogen Kininogen
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Structural Form Single Chain, High Molecular Weight
Species Human
Recombinant Native
Form Liquid
Purity or Quality Grade ≥95%
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