MilliporeSigma Osteopontin, HisTag, Mouse, Recombinant Protein, Mouse
Manufacturer: MilliporeSigma 49926050UG
DescriptionRecombinant, mouse osteopontin fused at the C-terminus to a His·Tag sequence and expressed in NSO-derived Leu17-Asn294 (Glu99Gly) murine myeloma cells. A secreted, highly acidic, Ca2+-binding, RGD-containing, phosphorylated glycoprotein. Chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. Has been shown to inhibit nitric oxide production and cytotoxicity by activated macrophages. Plays a significant role in inducing granulomas of various origin. OPN is also involved in the migration of embryonic fibroblasts, macrophages, and metastatic cells.
|Reconstitute to ≥100μg/mL with sterile PBS.|
|Lyophilized from 0.2μM sterile-filtered PBS, 50μg BSA/μg rmOPN.|
|Following reconstitution, aliquot and freeze (−70°C). Stock solutions are stable for up to 1 month at 4°C and for up to 3 months at −70°C. Avoid freeze/thaw cycles of stock solutions.|
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