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MilliporeSigma™ Osteopontin, HisTag™, Mouse, Recombinant Protein, Mouse

Manufacturer:  MilliporeSigma™ 49926050UG

Catalog No. 49-926-050UG


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Description

Description

Recombinant, mouse osteopontin fused at the C-terminus to a His·Tag™ sequence and expressed in NSO-derived Leu17-Asn294 (Glu99Gly) murine myeloma cells. A secreted, highly acidic, Ca2+-binding, RGD-containing, phosphorylated glycoprotein. Chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. Has been shown to inhibit nitric oxide production and cytotoxicity by activated macrophages. Plays a significant role in inducing granulomas of various origin. OPN is also involved in the migration of embryonic fibroblasts, macrophages, and metastatic cells.
Specifications

Specifications

Lyophilized
Reconstitute to ≥100μg/mL with sterile PBS.
≥95%
Osteopontin
RUO
Mouse
Lyophilized from 0.2μM sterile-filtered PBS, 50μg BSA/μg rmOPN.
SDS-PAGE
50μg
Following reconstitution, aliquot and freeze (−70°C). Stock solutions are stable for up to 1 month at 4°C and for up to 3 months at −70°C. Avoid freeze/thaw cycles of stock solutions.
His·Tag™
Yes
Documents
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