MilliporeSigma™ p53, HisTag™, Human, Recombinant Protein, E. coli

Manufacturer:  MilliporeSigma™ 50616510UG

Catalog No. 50-616-510UG

Description

Recombinant, human, wild-type p53 fused at the N-terminus to a His·Tag™ sequence and expressed in E. coli. p53, a tumor suppressor, blocks transformation and inhibits tumor cell growth. Numerous mutations in the p53 gene have been characterized in human cancers. Loss or mutation of p53 function is highly correlated with tumorigenesis. The purified protein is useful in DNA binding assays and as a protein kinase substrate.

Specifications

• Concentration: Concentration on Label
• Formulation: In 50mM KCl, 30mM sodium pyrophosphate, 5% glycerol, pH 7.5.
• Purity: ≥80%
• Source: E. coli
• Storage Requirements: Following initial thaw, aliquot and freeze (−70°C).
• Conjugate: His·Tag™
• Recombinant: Yes

• Format: Liquid
• Purification Method: SDS-PAGE
• Quantity: 10μg
• Immunogen: p53
• Regulatory Status: RUO
• Host Species: Human