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MilliporeSigma™ p53, HisTag™, Human, Recombinant Protein, E. coli

Manufacturer:  MilliporeSigma™ 50616510UG

Catalog No. 50-616-510UG

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Recombinant, human, wild-type p53 fused at the N-terminus to a His·Tag™ sequence and expressed in E. coli. p53, a tumor suppressor, blocks transformation and inhibits tumor cell growth. Numerous mutations in the p53 gene have been characterized in human cancers. Loss or mutation of p53 function is highly correlated with tumorigenesis. The purified protein is useful in DNA binding assays and as a protein kinase substrate.
Specifications

Specifications

Concentration on Label
In 50mM KCl, 30mM sodium pyrophosphate, 5% glycerol, pH 7.5.
≥80%
E. coli
Following initial thaw, aliquot and freeze (−70°C).
His·Tag™
Yes
Liquid
SDS-PAGE
10μg
p53
RUO
Human
SDS
Documents
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